私密秀场直播

姓名： 王婷婷 职务： 职称： 副教授 政治面貌： 中共党员 最高学历学位： 博士、研究生 专业: 药学 所属院系: 药学院 研究方向: 天然药物化学 电话: 信箱: [email protected] 个人主页:

个人简介

王婷婷博士，毕业于南京大学生命科学学院，获药学博士学位。研究方向聚焦特境微生物天然产物发现及功能研究。建立从真菌分离、产物获取及药用评价完整的技术体系，发现了大量结构新颖的活性天然产物。主持国家、浙江省和宁波市自然科学基金等纵向科研项目多项。获得4项国家发明专利授权。在天然药物化学领域权威期刊Chinese Chemical Letters、Organic Letters和Journal of Natural Products等以第一作者或通讯作者发表高水平论文10余篇，其中2篇被评为封面文章，多个新骨架分子被本领域顶级期刊Natural Product Reports评为热点分子，受到国内外同行关注。

学习和工作经历

2018.06—今 私密秀场直播 助理研究员、讲师、副教授

2014.09—2018.06 南京大学药学博士

2011.09—2014.06 私密秀场直播 理学硕士

2006.09—2011.06 天津农学院农学学士

近年发表的主要论文

[1] Yuying Liu; Tingting Wei; Guangjun Ran; Xiaohui Li; Tao Cai; Chanting Lai; Hongkun Wang; Bin Wu; Haixiao Jin; Weiyan Zhang; Tingting Wang*, Shan He*. α-Pyrones, Root Growth Inhibitors from a Mesophotic Zone Sponge-Associated Fungus Purpureocillium sp. NBUF263. Phytochemistry Letters 2025, 102944.

[2] Guangjun Ran; Ping Wang; Hongkun Wang; Tingting Wei; Yuying Liu; Haixiao Jin; Tingting Wang*; and Shan He*. Beautoide A, an Anti-Osteoclastogenic Sterol from Beauveria sp. NBUF147 Associated with an Irciniidae Sponge from the Marine Mesophotic Zone. Chemistry & Biodiversity 2024, e202401689.

[3] Tingting Wang; Yunping Feng; Jian Huang; Sitong Wu; Kun Hu; Jiabin Wu; C. Benjamin Naman; Hong Wang; Wenhan Lin; Shan He*. Pestanoid A, a Rearranged Pimarane Diterpenoid Osteoclastogenesis Inhibitor from a Marine Mesophotic Zone Chalinidae Sponge-Associated Fungus, Pestalotiopsis sp. NBUF145, Journal of Natural Products 2024, 87, 160-165.

[4] Tingting Wang; Jiaxin Tian; Jian Huang; Ye Yuan; C. Benjamin Naman; Sitong Wu; Hong Wang; Wenhan Lin; Zhiwu Tong; Lijian Ding; Weiyi Wang*; Shan He*. Irpetones A and B, Anti-Osteoclastic Heptaketides from a Marine Mesophotic Zone Ircinia Sponge-Associated Fungus Irpex sp. NBUF088, Journal of Natural Products 2024, 87, 1203−1208.

[5] Zhiwu Tong; Tingting Wang; Pei Yang; Jialin Sun; Chenpeng Zhang; Salman Khan; Xincun Wang; Ruihua Jiao; Huiming Ge; Wenying Zhuang; Gang Hu*; Renxiang Tan*. Acatulides A-G, neuroprotective macrolides from Acaulium album H-JQSF. Chinese Chemical Letters 2024, 35, 108488.

[6] Tingting Wang; Jiabin Zou; Te Li; Peng Shao; Wenli Zhou; Qiliang Lai; Yunping Feng; C. Benjamin Naman; Xiaojun Yan; Shan He*. Dendronecholones A‒D, New Anti-Vibrio Steroids Isolated from East China Sea Dendronephthya Soft Coral. Aquaculture 2022, 549, 737727.

[7] Yunping Feng; Hongkun Wang; Jialing Wu; Peng Shao; Wenli Zhou; Qiliang Lai; Houwen Lin; C. Benjamin Naman; Tingting Wang*; Shan He*. Acremocholone, an Anti-Vibrio Steroid from the Marine Mesophotic Zone Ciocalypta Sponge‐Associated Fungus Acremonium sp. NBUF150. Chemistry & Biodiversity 2022, 19, e202200028.

[8] Jiabin Zou; Jialing Wu; Lijian Ding; Weiyi Wang; Yinghui Liu; Yunping Feng; Qiliang Lai; Wenhan Lin; Tingting Wang; Shan He*. Guignardones Y–Z, Antiviral Meroterpenes from Penicillium sp. NBUF154 Associated with a Crella Sponge from the Marine Mesophotic Zone. Chemistry & Biodiversity 2022, 19, e202200475.

[9] Tingting Wang; Jing Zhou; Jiabin Zou; Yutong Shi; Wenli Zhou; Peng Shao; Tianze Yu; Wei Cui; Xiaohui Li; Xingxin Wu; Jing Ye; Xiaojun Yan; C. Benjamin Naman*; J. Enrico H. Lazaro and Shan He*. Discovery of Cymopolyphenols A–F from a Marine Mesophotic Zone Aaptos Sponge-Associated Fungus Cymostachys sp. NBUF082. Frontiers in Microbiology 2021, 12, 638610.

[10] Hairong Zhang; Jiabin Zou; Xiaoxue Yan; Junlong Chen; Xiujiao Cao; Jialing Wu; Yinghui Liu and Tingting Wang*. Marine-Derived Macrolides 1990–2020: An Overview of Chemical and Biological Diversity. Marine Drugs 2021, 19, 180.

[11] Jing Zhou; Hairong Zhang; Jing Ye; Xingxin Wu; Weiyi Wang; Houwen Lin; Xiaojun Yan; J. Enrico H. Lazaro; Tingting Wang*; C. Benjamin Naman; Shan He*. Cytotoxic Polyketide Metabolites from a Marine Mesophotic Zone Chalinidae Sponge-Associated Fungus Pleosporales sp. NBUF144. Marine Drugs 2021, 19, 186.

[12] Ye Yuan; Te Li; Tingting Wang*; C. Benjamin Naman; Jing Ye; Xingxin Wu; J. Enrico H. Lazaro; Xiaojun Yan*; Shan He*. Targeted Isolation of a Cytotoxic Cyclic Hexadepsipeptide from the Mesophotic Zone Sponge-Associated Fungus Cymostachys sp. NBUF082. Marine Drugs 2021, 19, 565.

[13] Ye Yuan; Xiaoping He; Tingting Wang; Xingwang Zhang; Zhong Li; Xiaoqing Xu; Weiyan Zhang; Xiaojun Yan; Shengying Li*; Shan He*. Efficient Preparation of Bafilomycin A1 from Marine Streptomyces lohii Fermentation Using Three-Phase Extraction and High-Speed Counter-Current Chromatography Marine Drugs 2020, 18, 332.

近年主持/参与的项目

1. 宁波市自然科学基金， 一般项目，基于基因组信息定向挖掘海洋中光层海绵共附生真菌Pyrenochaeta sp. NBUF199次级代谢产物及其抗骨质疏松活性研究，在研，主持。

2. 国家重点实验室，开放基金，高效发掘中光层海绵共附生真菌抗急性淋巴细胞白血病活性次级代谢产物，在研，主持。

3. 国家自然科学基金,青年项目，西沙群岛中光层海绵共附生真菌活性次级代谢产物的深度挖掘，结题，主持。

4. 国家自然科学基金，面上项目，新型隐球菌完整细胞中莢膜原位组成和相互作用检测的固体核磁共振新方法，结题，参加。

5. 浙江省基础公益研究计划项目，OSMAC策略与分子网络技术联用高效发掘海绵共附生真菌活性次级代谢产物，结题，主持。

6. 国家重点实验室，开放基金，2株西沙晋卿岛中光层海绵共附生真菌活性次级代谢产物的深度挖掘，结题，主持。

已获授权的发明专利

[1] 中国专利；王婷婷，何山，周静；一种氧杂蒽酮类化合物及其制备方法和用途；授权日，2022.5.17；ZL 202110258916.7。

[2] 中国专利；王婷婷，何山，周静；一种海绵共附生真菌及其在制备氧杂蒽醌类化合物中的应用；授权日，2023.11.14；ZL 202210078756.2。

[3] 中国专利；何山，王婷婷，冯芸萍；一种海绵共附生真菌及其在制备甾醇类化合物中的应用；授权日，2023,9,29；ZL 202210080188.X。

[4] 中国专利；何山，王婷婷，邹嘉斌；一种海绵共附生真菌及其在制备杂萜类化合物中的应用；授权日，2023,8.18；ZL 202210513117.4。

著作编写

略

学术兼职

浙江省药学会海洋药物专业委员会青年委员